Composed of **~50 proteins** (e. Bind to **inner kinetochore** (constitutive) and **outer kinetochore** (microtubule attachment). Kinesin-5 (Eg5): Slides antiparallel microtubules apart (inhibited by **taxanes** . Spindle fibers are **microtubule-based structures** essential for **chromosome segregation** during cell division. They form the **mitotic spindle**, pulling sister chromatids apart to ensure genetic stability. It is referred to as the mitotic spindle during mitosis, a process that produces genetically identical daughter cells, or. Spindle fibers are crucial components of cell division, ensuring the accurate and equal segregation of chromosomes to daughter cells. Cell division, the. the genome to the two daughter cells during division. Recent work has begun to uncove the molecular mechanisms behind.
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